Reye's Syndrome Awareness Month
United States
About
Reye’s Syndrome Awareness Month is observed throughout September to raise understanding of Reye’s syndrome, a rare but serious condition that can cause swelling in the liver and brain, most often affecting children and teenagers recovering from a viral infection. The observance helps families recognize warning signs, learn about prevention, and understand why aspirin should not be given to children or teenagers unless specifically directed by a healthcare professional.
Throughout the month, communities are encouraged to share reliable health information, support affected families, and promote prompt medical attention when concerning symptoms arise. By increasing awareness and encouraging informed conversations with healthcare providers, Reye’s Syndrome Awareness Month helps protect young people and highlights the importance of careful, informed care during recovery from illness.
History
Reye’s Syndrome Awareness Month is observed throughout September to promote understanding of Reye’s syndrome, a rare but potentially life-threatening condition that can cause sudden swelling of the liver and brain. The syndrome was first described in 1963 by Australian pathologist Dr. R. Douglas Reye and colleagues, whose report documented the distinctive combination of acute encephalopathy and fatty degeneration of the liver in children. Its early recognition helped distinguish Reye’s syndrome from other serious childhood illnesses involving vomiting, confusion, seizures, or loss of consciousness.
The observance developed alongside growing medical and public awareness of a possible association between Reye’s syndrome and the use of aspirin or other salicylate-containing medicines during viral illnesses in children and teenagers. During the 1970s and 1980s, health authorities and medical organizations increasingly advised against giving aspirin to young people with conditions such as influenza or chickenpox unless directed by a physician. These warnings, together with improved diagnosis and public education, contributed to a substantial decline in reported cases in several countries.
Over time, September became a period for sharing information about symptoms, risk reduction, and the importance of seeking urgent medical care when a child develops persistent vomiting, unusual sleepiness, confusion, or behavioral changes after a viral infection. Awareness efforts also emphasize reading medicine labels carefully and consulting health professionals about appropriate treatments for children. Because Reye’s syndrome can progress rapidly, education remains an important part of prevention and early recognition.
Culturally, Reye’s Syndrome Awareness Month gives families affected by the illness an opportunity to remember those who experienced it and to encourage broader knowledge of a condition that is now uncommon but still serious. Its continuing observance reflects the role of public-health communication in translating medical research into everyday safety practices, particularly concerning medication use in children.